Cosmetic Services – Skin Treatments
SCULPTRA
Sculptra works beneath the skin to stimulate natural collagen production, helping restore volume, improve firmness, and enhance overall skin quality over time. Our comprehensive guide will walk you through everything you need to know about the procedure.
What is SCULPTRA?
“SCULPTRA” is an injectable collagen-stimulating substance containing PLLA (Poly-L-Lactic Acid) particles. It stimulates collagen production, plumps, and lifts the face, with effects lasting up to 2 years. It particularly targets the production of Collagen Type I, one of the more than 16 types of collagen produced by the body, accounting for over 90% of all collagen in the body. Collagen helps improve elasticity, aids in wound healing, and is found in the skin, hair, bones, tissues, and blood vessel walls. SCULPTRA can stimulate up to 66.5% increase in Collagen Type I production after 3 months.
PLLA is considered the first collagen-stimulating substance, or “biostimulator,” to be approved by the U.S. Food and Drug Administration (FDA) in 1999. It is a synthetic substance derived from natural plants, has no side effects, is safe, and is biodegradable. It is used in the production of dissolvable sutures, screws, and plates used for bone fixation. It helps restore the deep layers of the skin to lift and reduce wrinkles, making the skin appear younger than its actual age.
How SCULPTRA Works
SCULPTRA is a collagen-stimulating treatment designed to restore skin strength and volume from within. Before injection, SCULPTRA is mixed with sterile water and carefully injected into the subcutaneous layer of the skin, commonly in areas such as the temples, cheeks, and beneath the cheekbones, where volume loss and aging are most noticeable.
Once injected, the solution spreads evenly through the skin. Its active ingredient, Poly-L-Lactic Acid (PLLA), stimulates fibroblast cells—the cells responsible for producing collagen and elastin. These essential proteins help support the dermis, the skin’s middle layer, improving firmness, elasticity, and overall skin structure over time.
As PLLA is gradually broken down by the body, it converts into lactic acid, a compound related to AHA. This process supports gentle skin renewal while activating macrophages, a type of white blood cell that helps trigger collagen synthesis. Although the PLLA itself slowly dissolves, the newly formed collagen remains, continuing to strengthen the skin.
The result is a gradual, natural improvement in skin quality. Fine lines soften, wrinkles become less noticeable, and deep folds appear smoother and more refined. Many patients begin to feel changes as early as the first few weeks, with collagen production continuing to improve progressively over time.

Skin sagging and loss of firmness occur when the skin becomes weak and loses its natural elasticity, leading to visible fine lines and wrinkles.

SCULPTRA is carefully injected beneath the skin at a depth of approximately 1.5–2 millimeters, targeting the deeper layers where collagen production begins.

By stimulating natural collagen from within, SCULPTRA helps restore a more youthful appearance and gradually softens the look of wrinkles for smoother, firmer skin.
SCULPTRA Injection Procedure
1. Skin Assessment
A thorough consultation is conducted by a dermatologist to evaluate your skin condition and determine a personalized treatment plan.
2. Numbing Application
A topical numbing cream is applied to the treatment area for approximately 45 minutes to help minimize discomfort during the procedure.
3. Product Preparation
SCULPTRA is prepared in its active form by mixing it with sterile water, ensuring proper consistency for effective treatment.
4. Injection Process
The solution is precisely injected beneath the skin at a depth of 1.5–2 mm using a 22–25 G blunt cannula for enhanced safety and accuracy.
5. Post-Injection Massage
A gentle facial massage is performed to help evenly distribute the product and support collagen stimulation within the skin.
Results After SCULPTRA
- Stimulates natural collagen production for gradual skin rejuvenation
- Helps reduce fine lines and wrinkles
- Improves skin firmness, smoothness, and elasticity
- Enhances hydration for a more radiant, youthful look
- Results develop progressively and can last over 2 years
Post-Treatment Care
- Mild redness, swelling, or bruising may occur (similar to fillers)
- Usually subsides within a few hours to 2–3 days
- Some may experience bruising for up to 2 weeks
Aftercare Tips:
- Apply cold compress to reduce swelling
- Avoid heavy exercise for 24 hours
- Avoid direct sun exposure for 24 hours
- Makeup can be applied after 2–3 hours
- Other treatments in the same area after 4 weeks
- Consult a doctor if unusual pain or skin color changes occur
Who is SCULPTRA Suitable For?
- Sagging skin, loss of firmness, and visible wrinkles
- Deep lines (forehead, under eyes, nasolabial folds, chin)
- Skin aging from age, stress, or lack of sleep
- Those who prefer natural, gradual results
- Those seeking long-lasting improvement (2+ years)
- Dull, dry skin needing hydration and radiance
- Individuals looking for a safe, clinically approved treatment
PRICE AND PACKAGES
Procedure | Price (THB) | Description |
Sculptra | 35,000 | 1 bottle |
Sculptra | 68,000 | 2 bottles |
Take the first step and reach out to us for a complimentary virtual consultation. Our virtual consultants and surgeons will provide personalized recommendations based on your unique needs. Every client is different, and we tailor each procedure to match your individual requirements.
Frequently Asked Questions
How is SCULPTRA different from fillers?
SCULPTRA works by gradually stimulating collagen production, so results appear over 4–6 weeks, while fillers provide immediate volume. It focuses on improving skin structure from within, whereas fillers simply add hyaluronic acid to fill areas. SCULPTRA results can last around 2 years, longer than fillers which typically last up to 1 year, and usually requires 2–3 sessions instead of a single treatment.
How many SCULPTRA sessions are needed?
The number of sessions depends on the individual’s skin condition and concerns. Most people require 1–4 sessions, with 2–3 sessions being the most common, spaced 6–8 weeks apart for optimal results.
What’s the difference between SCULPTRA and Rejuran?
SCULPTRA contains PLLA derived from plant-based materials and focuses on stimulating collagen for lifting, firmness, and wrinkle reduction.
Rejuran, on the other hand, contains polynucleotides (PN) from salmon DNA, which help repair damaged skin, improve texture, and support skin healing. SCULPTRA is more suitable for volume and lifting, while Rejuran is ideal for skin recovery and overall skin quality.
Who should avoid SCULPTRA?
SCULPTRA is not recommended for individuals under 18 years old, those who are pregnant or breastfeeding, people taking immunosuppressive medications, or those with allergies to its components. It should also be avoided by individuals with autoimmune conditions, active skin infections in the treatment area, or those with bleeding disorders or taking blood-thinning medications such as Aspirin or Warfarin.
